Methamphetamine and the hypothalamic-pituitary-adrenal axis
نویسندگان
چکیده
Psychostimulants such as methamphetamine (MA) induce significant alterations in the function of the hypothalamic-pituitary-adrenal (HPA) axis. These changes in HPA axis function are associated with altered stress-related behaviors and might contribute to addictive processes such as relapse. In this mini-review we discuss acute and chronic effects of MA (adult and developmental exposure) on the HPA axis, including effects on HPA axis associated genes/proteins, brain regions, and behaviors such as anxiety and depression. A better understanding of the mechanisms through which MA affects the HPA axis may lead to more effective treatment strategies for MA addiction.
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متن کاملErratum on: Methamphetamine and the hypothalamic-pituitary-adrenal axis
[This corrects the article on p. 178 in vol. 9, PMID: 26074755.].
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